Viral Infection Prevents Hemolytic Transfusion Reactions Following Incompatible Red Blood Cell Transfusion

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Hemolytic Transfusion Reactions.

SUMMARY: The risk of hemolytic transfusion reactions (HTRs) is approximately 1:70,000 per unit. Acute HTRs occurring during or within 24 h after administration of a blood product are usually caused by transfusion of incompatible red blood cells (RBCs), and, more rarely, of a large volume of incompatible plasma. Delayed HTRs are caused by a secondary immune response to an antigen on the donor's ...

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Hemolytic transfusion reactions

A hemolytic transfusion reaction (HTR) is the accelerated clearance or lysis of transfused red cells because of immunologic incompatibility. Although they may at times have similar clinical presentations, HTR is distinguished from autoimmune hemolysis or nonimmune causes of shortened survival of transfused red cells. HTR may occur when antigen-positive red cells are transfused to a patient with...

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Delayed hemolytic transfusion reactions.

Delayed hemolytic transfusion reactions continue to occur in spite of the use of all of the currently available techniques of antibody detection. Both low titers of the antibodies and dosage effects appear to contribute to the failure of detection. A rapid anamnestic response can occur with transfusion of the appropriate antigen. The clinical as well as the laboratory presentation of delayed he...

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Hemolytic reactions produced in dogs by transfusion of incompatible dog blood and plasma; renal aspects following whole blood transfusions.

By LAWRENCE E. YOUNG, M.D., DONALD M. ERVIN, M.D., AND CHARLES L. YUILE, M.D. H EMOLYTIC transfusion reactions occur more frequently than is generally appreciated and their incidence can be expected to increase for some time as the distribution of blood is facilitated. Many are doubtless overlooked because the outward manifestations may not be particularly striking, especially in anesthetized p...

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Allogeneic Red Blood Cell Transfusion Following the Total Hip Arthroplasty Triggers the Immunomodulatory Responses

Background and Aims: Total hip arthroplasty (THA) is a common orthopedic surgery. The main focus in the research of THA is immune responses in these patients following the blood transfusion.Therefore, in this study, we evaluated the immune modulation indexes such as T cell amplification, Tcell surface markers and also production of cytokines in the patients undergoing THA surgery following bloo...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2017

ISSN: 0002-9173,1943-7722

DOI: 10.1093/ajcp/aqw191.036